Thermoresponsive systems composed of poloxamer 407 and HPMC or NaCMC: mechanical, rheological and sol-gel transition analysis
نویسندگان
چکیده
منابع مشابه
Mechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel.
The aims of this study were to prepare a thermosensitive composite hydrogel (TCH) by mixing 24% (w/v) poloxamer 407 (P407), 16% (w/v) poloxamer 188 (P188) and 0.1% (w/v) carbopol 940 (C940), and to determine the effect of natural borneol/ (2-hydroxypropyl)-β-cyclodextrin (NB/HP-β-CD) inclusion complex on the phase transition temperature, mechanical, rheological properties, and release behaviors...
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The main objective of this work is to characterize the rheological behavior of poloxamer 407 solutions and gels in various shear flow fields.
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The use of poloxamers (PL) have been one of the most widely strategies used for drug delivery systems. The copolymer Poloxamer 407 is a non-ionic surfactant consisting of polioxyethylene (POE) and polioxypropylene (POP) that has many pharmaceutical applications due to its thermoreversible properties. PL are biocompatible and for this reason, are very attractive as carrier systems for administra...
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ژورنال
عنوان ژورنال: Carbohydrate Polymers
سال: 2020
ISSN: 0144-8617
DOI: 10.1016/j.carbpol.2020.116268